Active immunisation of dogs from 6 weeks of age: - to prevent mortality and clinical signs caused by canine distemper virus, - to prevent mortality and clinical signs caused by canine adenovirus type 1, - to prevent clinical signs and reduce viral excretion caused by canine adenovirus type 2, - to prevent clinical signs, leucopoenia and viral excretion caused by canine parvovirus, - to prevent clinical signs (nasal and ocular discharge) and reduce viral excretion caused by canine parainfluenza virus, - to prevent clinical signs, infection and urinary excretion caused by L.interrogans serogroup Australis serovar Bratislava, - to prevent clinical signs and urinary excretion and reduce infection caused by L.interrogans serogroup Canicola serovar Canicola and L.interrogans serogroup Icterohaemorrhagiae serovar Icterohaemorrhagiae, - to prevent clinical signs and reduce infection and urinary excretion caused by L.kirschneri serogroup Grippotyphosa serovar Grippotyphosa. Onset of immunity - 3 weeks after the first vaccination for CDV, CAV, CPV. - 3 weeks after completion of the primary course for CPiV and - 4 weeks after completion of the primary course for Leptospira components. Duration of immunity At least three years following the primary vaccination course for CDV, CAV-1, CAV-2 and CPV. The duration of immunity against CAV-2 was established by serology. At least one year following the primary vaccination course for CPiV and Leptospira components. Primary vaccination scheme Two doses of Versican Plus DHPPi/L4 3–4 weeks apart from 6 weeks of age. Re-vaccination scheme A single dose of Versican Plus DHPPi/L4 can be given every 3 years. Annual re-vaccination is required for parainfluenza and Leptospira components; therefore a single dose of compatible vaccine Versican Plus Pi/L4 can be used annually as required.
