112230
Cloprostenol is a synthetic prostaglandin analogue structurally related to Prostaglandin F2α (PGF2α), for use in cattle and horses. As a potent luteolytic agent it causes functional and morphological regression of the corpus luteum (luteolysis) in cattle and horses followed by return to oestrus and normal ovulation. Note There is a refractory period of four to five days after ovulation when cattle and horses are insensitive to the luteolytic effect of prostaglandins. Estrumate has a good safety margin and does not impair fertility. No deleterious effects have been reported on the progeny conceived at the oestrus following treatment. Cattle: • Suboestrus or non-detected oestrus • Induction of parturition • Termination of normal pregnancy • Termination of abnormal pregnancy • Mummified foetus • Hydrops of the foetal membranes • Chronic endometritis (pyometra) • Ovarian luteal cysts • Controlled breeding Cattle: 2ml in lactating cattle. The treatment must be administer immediately after milking. Administer by intramuscular injection observing normal aseptic precautions. Care should be taken to avoid injection through wet or dirty areas of skin. Withdrawals: Cattle: Meat 1day, Milk 0 hours
