130570
For the active immunisation of pregnant cows and heifers to raise antibodies against E. coli adhesin F5 (K99) antigen, rotavirus and coronavirus. While calves are fed colostrum from vaccinated cows during the first two to four weeks of life, these antibodies have been demonstrated to:
• reduce the severity of diarrhoea caused by E. coli F5 (K99);
• reduce the incidence of scours caused by rotavirus;
• reduce the shedding of virus by calves infected with rotavirus or coronavirus.
Onset of Immunity:
• Passive protection against all active substances will commence from the start of colostrum feeding.
Duration of Immunity:
• In calves artificially fed with pooled colostrum, protection will continue until colostrum feeding ceases.
• In naturally suckled calves, protection against rotavirus will persist for at least 7 days and against coronavirus for at least 14 days.
Dosage & Administration
Dose - 2 ml by intramuscular injection. The recommended site is the side of the neck. A single injection should be given during each pregnancy between 12 and 3 weeks before calving is expected.
Colostrum feeding
• Protection of calves depends on the physical presence of colostrum antibodies (from vaccinated cows) within the gut for the duration of the first 2 - 3 weeks of life until calves develop their own immunity. Thus it is essential to ensure adequate colostrum feeding for the whole of this period to maximise the efficacy of vaccination. All calves must receive adequate colostrum from their dams within 6 hours of birth. Suckled calves will continue to receive adequate colostrum naturally by feeding from vaccinated cows.
